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KMID : 0359320060460030271
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Korean Journal of Veterinary Research
2006 Volume.46 No. 3 p.271 ~ p.274
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Paratuberculosis in mouflon (ovis musimon): A case report
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배유찬
김하영/김희진/윤순식/박중원/진영화/조경오/강문일
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Abstract
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A 2-years-old female domesticated mouflon with a clinical history of chronic diarrhea and emaciation was submitted to NVRQS. Grossly, there were severe thickening of small intestine wall and enlargement of mesenteric lymph nodes. Microscopically, severe granulomatous inflammation was found in small and large intestine, mesenteric lymph nodes, spleen and liver. By Ziehl-Neelsen stain, innumerable acid-fast rod bacteria were found in the cytoplasm of epitheloid and Langhans type giant cells present in these organs. By PCR assay with primer pair specific for Mycobacterium avium subspecies paratuberculosis(IS 900) with small intestine sample, strong positive reaction was detected, although the organism was not isolated from this organ. Based on the results of histopathology and PCR, we concluded that the case was a typical paratuberculosis in mouflon. As far as we know, this is the first case report of paratuberculosis in mouflon Korea.
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KEYWORD
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Diarrhea, Johne`s disease, Mouflon, Mycobacterium avium subspecies paratuberculosis
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